HomeDNAGetting probably the most out of your new Large Y-700 outcomes

Getting probably the most out of your new Large Y-700 outcomes

The Large Y check modified to a very new expertise earlier this yr. It now covers 50% extra of the Y chromosome than beforehand. And so it’s anticipated that the brand new check will uncover extra SNP markers that the previous expertise didn’t detect. Moreover, the brand new SNPs ought to have the ability to extra precisely date the varied branching factors on the Tree of Mankind.

It additionally offers us roughly 700 STR markers whereas the earlier check solely gave roughly 500 STRs. Consequently, the previous check is named the Large Y-500 and the brand new one is named the Large Y-700. Going ahead, all new Large Y orders will use this new expertise.

For many who did the previous check, it’s potential to improve from the Large Y-500 to the Large Y-700. However for everybody who does the brand new check, or upgrades from the previous model to the brand new model, it’s important that you just add a replica of your outcomes to the Large Tree in order that we will get some important extra analyses. You’ll discover directions for doing so on the Large Tree web site right here and on the Y-DNA Knowledge Warehouse web site right here however I embrace a briefer abstract under.

What do you get out of your Outcomes?

Your outcomes ought to be analysed inside every week or two and you may test them by navigating to your explicit portion of the Large Tree. For members of Ryan Group 2 (for instance), their Terminal SNP is M756 and you’ll discover this department on the Large Tree right here (see screenshot under). The diagram properly illustrates their placement on the Tree of Mankind and the surnames of the folks sitting on neighbouring branches to their very own. This info will be very helpful for figuring out the geographic origins of your explicit direct male line and for figuring out in case your identify is related to an Historic Irish Clan.

Undertaking Directors can use programmes just like the SAPP instrument to generate Mutation Historical past Timber and decide the possible branching construction of your explicit “genetic household” from the time of surname origins as much as the current day. This course of may also assist determine which Ryan’s (for instance) are extra carefully associated to one another and that are extra distantly associated. It is usually potential to this point the branching factors throughout the Mutation Historical past Tree utilizing SNP knowledge in addition to STR knowledge. This course of is more likely to grow to be extra correct with the appearance of the brand new Large Y-700 knowledge and the identification of latest SNPs. It’s anticipated that the brand new knowledge will cut back the variety of “years per SNP” from about 130 to about 80 years per SNP. You may learn extra about this right here.

You may as well click on in your surname above your package quantity for an evaluation of your Distinctive / Personal SNPs. These might show helpful sooner or later for outlining new downstream branches within the Mutation Historical past Tree and for courting new branching factors. However this very a lot is dependent upon new folks becoming a member of the mission and enterprise Large Y-700 testing (in order that we will examine apples with apples). And as it is a new check, it’s possible that we must wait a while earlier than we start to see actual advantages from it.

Making a Hyperlink to your Large Y outcomes

To be able to create a downloadable hyperlink to your Large Y outcomes, first log in to your FTDNA account and go to your Large Y Outcomes web page …

Then click on on the blue Obtain Uncooked Knowledge button …

Then it is advisable to create a hyperlink to two separate information – your VCF file and your BAM file. The VCF file is used for putting you on The Large Tree. The BAM file is used for high-end technical evaluation by the parents on the Y-DNA Knowledge Warehouse. You may see a few of the outcomes thus far on their Protection Web page right here (and should you like you may seek for kits by surname, together with your individual).

1) to create a hyperlink to your VCF file, proper click on on the inexperienced Obtain VCF button, after which click on on “Copy hyperlink” from the drop-down menu. You’ll later paste this hyperlink into the the “Obtain URL” field on the Submission Kind.

Alternatively you may merely (left) click on on the inexperienced Obtain VCF button and this downloads a 10 MB file to your laptop. This may then be straight uploaded by way of the Submission Kind under. Nonetheless it’s preferable (and fewer problematic) to generate a hyperlink as a substitute.

2) to create a hyperlink to your BAM file, click on on the inexperienced Generate BAM button. You’ll then get a message that “Your Large Y BAM file is at the moment being generated” (see under). This generates a very giant BAM file … but it surely takes a number of days to arrange so you’ll have to come again to this web page in a couple of days time! Put a reminder in your diary / calendar!

Importing your VCF file

Having created the primary hyperlink (to your VCF file) and copied it, click on right here to go to the Y-DNA Knowledge Warehouse and fill within the type together with your customary info – e mail, package quantity, surname of your paternal MDKA (Most Distant Recognized Ancestor), and (most significantly) the hyperlink to your file – you do that by pasting the hyperlink you copied earlier into the “Obtain URL” field beneath the heading “Uncooked Knowledge Add” on the backside of the web page.

If you wish to add the precise file itself (fairly than a hyperlink), click on on the blue Direct tab below “Uncooked Knowledge Add” after which click on on the “Select File” button and fix the file from the place you downloaded it onto your laptop (on my laptop computer, the “Select File” button seems to be barely hidden below some textual content but it surely works should you click on on the beginning of the textual content). 

Remember to tick the checkbox to verify you agree with the Knowledge Coverage after which click on the blue Submit button.

Importing your BAM file

A number of days later, come again to this similar place to get a hyperlink to your newly generated BAM file. So, navigate to your Large Y Outcomes web page, and after clicking on the blue Obtain Uncooked Knowledge button, you’ll discover that the BAM file has been generated. DO NOT DOWNLOAD IT – you needn’t and it’s method too huge. As a substitute, click on on the inexperienced Share BAM button after which the inexperienced Copy button so as to copy a hyperlink to your BAM file. You’ll share this hyperlink within the subsequent step.

Then go to the Y-DNA Knowledge Warehouse and fill in the identical type as earlier than BUT …

  1. choose Different for the Testing Lab
  2. enter your Equipment ID Quantity 
  3. depart every thing else on its default setting
  4. paste the hyperlink to the BAM file within the “Obtain URL” field beneath the heading “Uncooked Knowledge Add”
  5. tick the checkbox to verify you agree with the Knowledge Coverage after which click on the blue Submit button

Maurice Gleeson

Aug 2019



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