Covalent natural nanosheets (CONs) are receiving large curiosity for his or her potential in versatile purposes. Nonetheless, the synthesis of CONs normally suffers from the usage of poisonous solvents, low yields and uncontrollable thickness. Right here, we report a inexperienced, excessive yield, and scalable technique to strip two-dimensional imine-linked covalent natural framework (COF) powders in water utilizing bi-functional ionic liquids as each the intercalator and stabilizer underneath ambient situations. It’s proven that the exfoliation yield reaches as much as 66.6%, which is a report worth for the delamination of CONs from bulk COF powder. The thickness of CONs is principally within the vary from 0.4 to 2.0 nm and the lateral dimension is massive up to some hundred nanometers. Importantly, the aqueous IL options might be reused and recycled for the exfoliation of CONs. The acid–base and hydrogen bond interactions between CONs and cations of the ILs are discovered to play crucial roles within the delamination and stability of CONs. Moreover, the CONs with none components akin to metals, photosensitizers, and sacrificial brokers have been used as catalysts for photocatalytic CO2 discount with gaseous water to yield CO within the gasoline section underneath visible-light irradiation. The manufacturing price of CO is 132.2 μmol g−1 h−1, which is twice that by the majority COF powder, and outperforms most visible-light pushed metal-free COFs reported to date. Due to this fact, the liquid section stripping method reported right here possesses large potentiality in mass manufacturing of CONs for top effectivity photocatalysis of CO2 discount within the gasoline section.